Day #29 Anticentromere Ab are Specific for CREST Syndrome
Scleroderma is also called systemic sclerosis and is characterized by inflammation that leads to progressive tissue fibrosis through excessive deposition of type I and type III colla- gen. It commonly manifests as CREST syndrome (limited form) and anticentromere antibodies are specific for the syndrome. RF and ANA can also be positive.
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