#50 FU my Sun!
5-FU is a pyrimidine analog used to treat colon and basal cell cancers. Side effects include photosensitivity and myelosuppression. Treat OD with thymidine.
No pictogram today, instead I’m putting up a little work in progress piece. It’s my followup to the gastric subway.
#49 PSC And UC
Ulcerative colitis is an inflammatory bowel disease characterized by ulcerations limited to the mucosa/submucosa yet always involving the rectum. Lesions are in a continuous fashion. It is associated with primary sclerosing cholangitis which is an idiopathic disorder characterized by inflammation, fibrosis, and strictures of the extra/intrahepatic bile ducts. Symptoms and signs include jaundice, pruritus, and fatigue. Alk phos and bilirubin is increased and multiple bile duct strictures with dilatations are seen with ERCP. Patients with UC have a markedly increased risk of colorectal cancer and patients with PSC have an increased rate of cholangocarcinoma.
Microcytic anemia is caused but iron deficiency and lead poisoning. B12 and folate (B9) cause megaloblastic macrocytic anemias.
Anonymous asked: Hi! I'm currently studying for my Step 1 and came across your tumblr. WoW! Your gastric subway is awesome. Thanks for posting it. may i ask for your permission, if i can share it with my friends in our FB step 1 group (and mentioning you :) ) thanks!
Thanks. Of course you can share it. Best of luck with step 1.
Anonymous asked: How old are you? You are a very talented person! Thank you for sharing your love of art and your love of medicine.
Thanks, I appreciate it. I’m 27. I started medical school after taking a year to do architecture after college.
In celebration of all these awesome new followers I’m taking a vacation to Ohio. Well actually, I’m heading to a wedding in Cleveland until monday night. I probably won’t have time to post daily drawings until I get back but I’ll try to catch up then.
Day #47 PTH
Parathyroid hormone acts to increase bone resorption of calcium and phosphate. It also increases kidney resorption of calcium in the DCT while decreasing resorption of phosphate. 1,25 OH2 vitamin D production is increased via 1 alpha hydroxylase. The net effect is increased serum calcium, urine phosphate, and decreased serum phosphate.
Day #46 Malnutrition
When children are malnourished they first lose weight, then they start losing ground on length and then on head circumference.
inarsvitae asked: your Gastric Subway is absolutely amazing/elegant/beautiful. (As are your daily medical visualizations). Any plans to do any more "Anatomy Subway" work? It deserves a whole series!
Thanks. Right now i’m tied up with my current daily project but in about 2 months I’ll take the boards and the project will cease to have utility for me. After that I’m sure I’ll return to larger projects, more like the gastric subway, and continuing to practice figure drawing.
awessumpossum asked: Wow! You're so creative! I'm also very interested in art (I'm more of a digital painter) and medicine too, but I haven't really posted my stuff on Tumblr. I've actually been thinking about starting a daily sketch, and your awesome daily project has really motivated me. If I could ask, which program(s) do you use for your designs?
You should definitely start a project. I’ve been a big fan of daily projects because they make you just put something down, even on the days you don’t feel like you have anything creative to say. Often I have made the best work on those days
I’m pretty much an adobe illustrator kind of guy. For figure drawing I use my wacom intuos tablet but for vector stuff (my current project and the gastric subway) I just use a mouse. Sometimes I’ll tinker a bit in photoshop after exporting the vectors. My ophthalmology project was mostly in photoshop.
Best of luck and I hope that you start drawing and posting.
Many thanks for medicalstate for the feature. I’m pretty new to actually posting on tumblr and I didn’t even realize there was a tumblr radar/spotlight. Regardless I’m quite flattered and wanted to say hello to all the new followers. Hopefully you’ll find my new daily project on visualizing medicine boards facts interesting. Stop by to say hello at any point, I’m always happy to chat.
Above the fold.
This afternoon, I checked into Tumblr to find a spike of activity on my dashboard. I have learned through my own stumbling and by word of mouth that my recent feature of Steven McGaughey’s the Gastric Subway has been featured on the Tumblr Spotlight.
I just want to take this opportunity to thank everyone for taking interest in the blog, to the staff at Tumblr for the feature, and last but not least to Steven McGaughey, who kindly allowed me to post his art on here. Please do check out his other works on his blog and on his website.
To all of the new followers, welcome to the blog. I hope you enjoy what you see and what you read. Expect more updates as I continue this journey. Thanks again for your interest and take care.
Tom of the Medical State of Mind
Day #46 SIADH
SIAHD causes euvolemic hyponatremia resulting from increased AHD release independent of serum osmolality. It is associated with CNS disease, pulmonary disease (pneumonia, sarcoid), and small cell carcinoma. Diangosis is based of a urine osmolality >50-100 with a urinary sodium > 20 (demonstrating patient is not hypovolemic). Treatment is fluid restriction and demeclocycline.
Day #45 Diabetes Insipidus
Individuals with diabetes insipidus, or DI (Die/Dice) prefer ice cold beverages for unknown reasons. These patients present with polydispsia, polyuria, and persistent thirst due to an inability to concentrate urine. There is a central DI where the posterior pituitary failed to secrete ADH or nephrogenic DI where the kidneys fail to respond to ADH. Causes of central DI include tumor and Sheehan’s syndrome (ischemia) and lithium/demeclycycline for nephrogenic DI.